Identification of microRNA as sepsis biomarker based on miRNAs regulatory network analysis.
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ABSTRACT:
SUBMITTER: Huang J
PROVIDER: S-EPMC3997997 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Publications
Identification of microRNA as sepsis biomarker based on miRNAs regulatory network analysis.
Huang Jie J Sun Zhandong Z Yan Wenying W Zhu Yujie Y Lin Yuxin Y Chen Jiajai J Shen Bairong B Wang Jian J
BioMed research international 20140406
Sepsis is regarded as arising from an unusual systemic response to infection but the physiopathology of sepsis remains elusive. At present, sepsis is still a fatal condition with delayed diagnosis and a poor outcome. Many biomarkers have been reported in clinical application for patients with sepsis, and claimed to improve the diagnosis and treatment. Because of the difficulty in the interpreting of clinical features of sepsis, some biomarkers do not show high sensitivity and specificity. MicroR ...[more]
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