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Ultrasonographic (TCS) and clinical findings in overlapping phenotype of essential tremor and Parkinson's disease (ET-PD).

ABSTRACT: BACKGROUND: Essential tremor (ET) and Parkinson's disease (PD) are considered distinct disorders. The aim of the study was to look for a link or any distinguishing features by transcranial sonography (TCS), together with the clinical examination findings in a group of patients with overlapping phenotype of ET and PD (ET-PD). METHODS: A prospective observational case-control study was carried out from the 3rd January 2011 until 30th January 2013 at the Hospital of Lithuanian University of Health Sciences. The final study group consisted of 15 patients with ET-PD, 116 patients with ET-only and 141 patients with PD-only. The control group included 101 subjects. Clinical diagnosis was of a diagnostic standard. RESULTS: The main ultrasonographic findings in the ET-PD group were similar to those of the PD-only: hyperechogenicity of the substantia nigra (66.7%, p?

SUBMITTER: Lauckaite K 

PROVIDER: S-EPMC3998107 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature

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Ultrasonographic (TCS) and clinical findings in overlapping phenotype of essential tremor and Parkinson's disease (ET-PD).

Laučkaitė Kristina K   Rastenytė Daiva D   Šurkienė Danguolė D   Vaidelytė Birutė B   Dambrauskaitė Gabrielė G   Sakalauskas Andrius A   Vaitkus Antanas A   Gleiznienė Rymantė R  

BMC neurology 20140322

<h4>Background</h4>Essential tremor (ET) and Parkinson's disease (PD) are considered distinct disorders. The aim of the study was to look for a link or any distinguishing features by transcranial sonography (TCS), together with the clinical examination findings in a group of patients with overlapping phenotype of ET and PD (ET-PD).<h4>Methods</h4>A prospective observational case-control study was carried out from the 3rd January 2011 until 30th January 2013 at the Hospital of Lithuanian Universi  ...[more]

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