Ontology highlight
ABSTRACT:
SUBMITTER: Silva RR
PROVIDER: S-EPMC3998140 | biostudies-literature | 2014 May
REPOSITORIES: biostudies-literature
Silva Ricardo R RR Jourdan Fabien F Salvanha Diego M DM Letisse Fabien F Jamin Emilien L EL Guidetti-Gonzalez Simone S Labate Carlos A CA Vêncio Ricardo Z N RZ
Bioinformatics (Oxford, England) 20140117 9
We present ProbMetab, an R package that promotes substantial improvement in automatic probabilistic liquid chromatography-mass spectrometry-based metabolome annotation. The inference engine core is based on a Bayesian model implemented to (i) allow diverse source of experimental data and metadata to be systematically incorporated into the model with alternative ways to calculate the likelihood function and (ii) allow sensitive selection of biologically meaningful biochemical reaction databases a ...[more]