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Methyl 3'-benzyl-4'-(2,4-di-chloro-phen-yl)-1'-methyl-2-oxo-spiro-[indoline-3,2'-pyrrolidine]-3'-carboxyl-ate.

ABSTRACT: In the title compound, C27H24Cl2N2O3, the indole ring system is essentially planar, with a maximum deviation of 0.082?(2)?Å for the carbonyl C atom. It makes a dihedral angle of 88.53?(6)° with the mean plane of the 4-methyl-pyrrolidine ring, which adopts an envelope conformation with the N atom at the flap position. The mol-ecular structure is stabilized by intra-molecular C-H?O hydrogen bonds, which generate S(6) and S(7) ring motifs, and an intra-molecular ?-? inter-action involving the benzyl and di-chloro-substituted benzene rings [centroid-centroid distance = 3.6291?(11)?Å]. In the crystal, mol-ecules are linked via N-H?O hydrogen bonds, forming C(7) chains running parallel to [10-1].

SUBMITTER: Karthikeyan S

PROVIDER: S-EPMC3998484 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature

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Methyl 3'-benzyl-4'-(2,4-di-chloro-phen-yl)-1'-methyl-2-oxo-spiro-[indoline-3,2'-pyrrolidine]-3'-carboxyl-ate.

Karthikeyan S S Narayanan P P Sethusankar K K Devaraj Anthonisamy A Bakthadoss Manickam M

Acta crystallographica. Section E, Structure reports online 20140222 Pt 3

In the title compound, C27H24Cl2N2O3, the indole ring system is essentially planar, with a maximum deviation of 0.082 (2) Å for the carbonyl C atom. It makes a dihedral angle of 88.53 (6)° with the mean plane of the 4-methyl-pyrrolidine ring, which adopts an envelope conformation with the N atom at the flap position. The mol-ecular structure is stabilized by intra-molecular C-H⋯O hydrogen bonds, which generate S(6) and S(7) ring motifs, and an intra-molecular π-π inter-action involving the benzy ...[more]

PMID: 24765030

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Methyl 3'-benzyl-4'-(2-chloro-phen-yl)-1'-methyl-2-oxo-spiro-[indoline-3,2'-pyrrolidine]-3'-carboxyl-ate.

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