Metastatic Renal Cancer: What Role for Everolimus?
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ABSTRACT:
SUBMITTER: Belibi FA
PROVIDER: S-EPMC3998839 | biostudies-literature | 2010 Feb
REPOSITORIES: biostudies-literature
Publications
Metastatic Renal Cancer: What Role for Everolimus?
Belibi Franck A FA Edelstein Charles L CL
Clinical medicine reviews in oncology 20100201
Metastatic renal cell carcinoma is uncommon (only 3% of cancers worldwide) but of poor prognosis. Renal cell carcinoma has traditionally been treated with cytokines (interferon-α or interleukin-2). More recently, a more clear understanding of the molecular and cellular mechanisms of the disease, involving the VEGF receptor and mTOR, has led to the discovery of novel therapies. Therapeutic options in patients with advanced RCC include the VEGF receptor inhibitors Sunitinib and Sorafenib, the anti ...[more]
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