Investigating the reactivities of a polyketide synthase module through fluorescent click chemistry.
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ABSTRACT:
SUBMITTER: Hughes AJ
PROVIDER: S-EPMC3999232 | biostudies-literature | 2014 May
REPOSITORIES: biostudies-literature
Publications
Investigating the reactivities of a polyketide synthase module through fluorescent click chemistry.
Hughes Amanda Jane AJ Tibby Matthew R MR Wagner Drew T DT Brantley Johnathan N JN Keatinge-Clay Adrian T AT
Chemical communications (Cambridge, England) 20131106 40
A method for monitoring in vitro polyketide synthesis has been developed whereby nonchromophoric polyketide products are made brightly fluorescent in a simple, rapid, inexpensive, and bioorthogonal manner through CuAAC with a sulforhodamine B azide derivative. ...[more]
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