Ontology highlight
ABSTRACT:
SUBMITTER: Silla JM
PROVIDER: S-EPMC3999868 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Silla Josué M JM Duarte Claudimar J CJ Cormanich Rodrigo A RA Rittner Roberto R Freitas Matheus P MP
Beilstein journal of organic chemistry 20140416
The gauche effect in fluorinated alkylammonium salts is well known and attributed either to an intramolecular hydrogen bond or to an electrostatic attraction between the positively charged nitrogen and the vicinal electronegative fluorine atom. This work reports the effect of adding a fluorine atom in 2-fluoroethylamine hydrochloride on the conformational isomerism of the resulting 2,2-difluoroethylamine chloride (2). The analysis was carried out using NMR coupling constants in D2O solution, in ...[more]