Ontology highlight
ABSTRACT:
SUBMITTER: Zehr EA
PROVIDER: S-EPMC3999902 | biostudies-literature | 2014 Apr
REPOSITORIES: biostudies-literature
Zehr Elena A EA Kraemer James A JA Erb Marcella L ML Coker Joanna K C JK Montabana Elizabeth A EA Pogliano Joe J Agard David A DA
Structure (London, England : 1993) 20140313 4
Tubulins are a universally conserved protein superfamily that carry out diverse biological roles by assembling filaments with very different architectures. The underlying basis of this structural diversity is poorly understood. Here, we determine a 7.1 Å cryo-electron microscopy reconstruction of the bacteriophage-encoded PhuZ filament and provide molecular-level insight into its cooperative assembly mechanism. The PhuZ family of tubulins is required to actively center the phage within infected ...[more]