Ontology highlight
ABSTRACT:
SUBMITTER: Jiang Y
PROVIDER: S-EPMC3999979 | biostudies-literature | 2011 Dec
REPOSITORIES: biostudies-literature
Jiang Yanan Y Xu Weijia W Thompson Lee Parnell LP Gutell Robin R RR Miranker Daniel P DP
Proceedings. IEEE International Conference on Bioinformatics and Biomedicine 20111201
We present a fast pairwise RNA sequence alignment method using structural information, named R-PASS (RNA Pairwise Alignment of Structure and Sequence), which shows good accuracy on sequences with low sequence identity and significantly faster than alternative methods. The method begins by representing RNA secondary structure as a set of structure motifs. The motifs from two RNAs are then used as input into a bipartite graph-matching algorithm, which determines the structure matches. The matches ...[more]