Ontology highlight
ABSTRACT:
SUBMITTER: Riahi R
PROVIDER: S-EPMC4000736 | biostudies-literature | 2014 Feb
REPOSITORIES: biostudies-literature
Riahi Reza R Long Min M Yang Yongliang Y Dean Zachary Z Zhang Donna D DD Slepian Marvin J MJ Wong Pak Kin PK
Integrative biology : quantitative biosciences from nano to macro 20140201 2
Collective cell behavior in response to mechanical injury is central to various regenerative and pathological processes. Using a double-stranded locked nucleic acid probe for monitoring real-time intracellular gene expression, we examined the spatiotemporal response of epithelial cells during injury-induced collective migration and compared to the blocker assay with minimal injury as control. We showed that cells ∼150 μm from the wound edge exhibit a gradient in response to mechanical injury, ex ...[more]