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Damping of monocular pendular nystagmus with vibration in a patient with multiple sclerosis.

ABSTRACT: Acquired pendular nystagmus (PN) occurs commonly in multiple sclerosis (MS) and results in a highly disabling oscillopsia that impairs vision. It usually consists of pseudo-sinusoidal oscillations at a single frequency (3-5 Hz) that often briefly stop for a few hundred milliseconds after saccades and blinks. The oscillations are thought to arise from instability in the gaze-holding networks ("neural integrator") in the brainstem and cerebellum.(1,2) Here we describe a patient with monocular PN in whom vibration on the skull from a handheld muscle massager strikingly diminished or stopped her nystagmus.

SUBMITTER: Beh SC 

PROVIDER: S-EPMC4001187 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature

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Damping of monocular pendular nystagmus with vibration in a patient with multiple sclerosis.

Beh Shin C SC   Tehrani Ali Saber AS   Kheradmand Amir A   Zee David S DS  

Neurology 20140314 15

Acquired pendular nystagmus (PN) occurs commonly in multiple sclerosis (MS) and results in a highly disabling oscillopsia that impairs vision. It usually consists of pseudo-sinusoidal oscillations at a single frequency (3-5 Hz) that often briefly stop for a few hundred milliseconds after saccades and blinks. The oscillations are thought to arise from instability in the gaze-holding networks ("neural integrator") in the brainstem and cerebellum.(1,2) Here we describe a patient with monocular PN i  ...[more]