Reduction in perceived stress as a migraine trigger: testing the "let-down headache" hypothesis.

ABSTRACT:

Objective

To test whether level of perceived stress and reductions in levels of perceived stress (i.e., "let-down") are associated with the onset of migraine attacks in persons with migraine.

Methods

Patients with migraine from a tertiary headache center were invited to participate in a 3-month electronic diary study. Participants entered data daily regarding migraine attack experience, subjective stress ratings, and other data. Stress was assessed using 2 measures: the Perceived Stress Scale and the Self-Reported Stress Scale. Logit-normal, random-effects models were used to estimate the odds ratio for migraine occurrence as a function of level of stress over several time frames.

Results

Of 22 enrolled participants, 17 (median age 43.8 years) completed >30 days of di

SUBMITTER: Lipton RB 

PROVIDER: S-EPMC4001194 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature