Ontology highlight
ABSTRACT:
SUBMITTER: Possin KL
PROVIDER: S-EPMC4001926 | biostudies-literature | 2013 Sep
REPOSITORIES: biostudies-literature
Possin Katherine L KL Kang Gail A GA Guo Christine C Fine Eric M EM Trujillo Andrew J AJ Racine Caroline A CA Wilheim Reva R Johnson Erica T ET Witt Jennifer L JL Seeley William W WW Miller Bruce L BL Kramer Joel H JH
Movement disorders : official journal of the Movement Disorder Society 20130711 10
The objective of this study was to investigate how acetylcholinesterase inhibitor (ChEI) treatment affects brain function in Parkinson's disease (PD). Twelve patients with PD and either dementia or mild cognitive impairment underwent task-free functional magnetic resonance imaging before and after 3 months of ChEI treatment and were compared with 15 age- and sex-matched neurologically healthy controls. Regional spontaneous brain activity was measured using the fractional amplitude of low-frequen ...[more]