Ontology highlight
ABSTRACT:
SUBMITTER: Soriano-Tarraga C
PROVIDER: S-EPMC4005764 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Soriano-Tárraga Carolina C Jiménez-Conde Jordi J Giralt-Steinhauer Eva E Mola Marina M Ois Angel A Rodríguez-Campello Ana A Cuadrado-Godia Elisa E Fernández-Cadenas Israel I Carrera Caty C Montaner Joan J Elosua Roberto R Roquer Jaume J
PloS one 20140430 4
Ischemic stroke (IS), a heterogeneous multifactorial disorder, is among the leading causes of mortality and long-term disability in the western world. Epidemiological data provides evidence for a genetic component to the disease, but its epigenetic involvement is still largely unknown. Epigenetic mechanisms, such as DNA methylation, change over time and may be associated with aging processes and with modulation of the risk of various pathologies, such as cardiovascular disease and stroke. We ana ...[more]