Ontology highlight
ABSTRACT:
SUBMITTER: Nwazue VC
PROVIDER: S-EPMC4005784 | biostudies-literature | 2014 May
REPOSITORIES: biostudies-literature
Nwazue Victor C VC Arnold Amy C AC Raj Vidya V Black Bonnie K BK Biaggioni Italo I Paranjape Sachin Y SY Orozco Carlos C Dupont William D WD Robertson David D Raj Satish R SR
Clinical and experimental pharmacology & physiology 20140501 5
Postural tachycardia syndrome (POTS) is characterized by excessive increases in heart rate (HR) upon standing. Previous studies have shown that standing HR decreases over time in POTS patients given placebo. We hypothesized that this reduction is due to cardiovascular physiological alteration, as opposed to psychological benefit from perceived therapy. To prospectively test this hypothesis, we examined the effects of an open-label 'no treatment' intervention (NoRx) compared with a patient-blinde ...[more]