Ontology highlight
ABSTRACT:
SUBMITTER: Domingo Meza-Aguilar J
PROVIDER: S-EPMC4005925 | biostudies-literature | 2014 Mar
REPOSITORIES: biostudies-literature
Domingo Meza-Aguilar J J Fromme Petra P Torres-Larios Alfredo A Mendoza-Hernández Guillermo G Hernandez-Chiñas Ulises U Arreguin-Espinosa de Los Monteros Roberto A RA Eslava Campos Carlos A CA Fromme Raimund R
Biochemical and biophysical research communications 20140212 2
Autotransporters (ATs) represent a superfamily of proteins produced by a variety of pathogenic bacteria, which include the pathogenic groups of Escherichia coli (E. coli) associated with gastrointestinal and urinary tract infections. We present the first X-ray structure of the passenger domain from the Plasmid-encoded toxin (Pet) a 100 kDa protein at 2.3 Å resolution which is a cause of acute diarrhea in both developing and industrialized countries. Pet is a cytoskeleton-altering toxin that indu ...[more]