Precise excision of the large pathogenicity island, SPI7, in Salmonella enterica serovar Typhi.
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ABSTRACT:
SUBMITTER: Bueno SM
PROVIDER: S-EPMC400632 | biostudies-literature | 2004 May
REPOSITORIES: biostudies-literature
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Precise excision of the large pathogenicity island, SPI7, in Salmonella enterica serovar Typhi.
Bueno Susan M SM Santiviago Carlos A CA Murillo Alejandro A AA Fuentes Juan A JA Trombert A Nicole AN Rodas Paula I PI Youderian Philip P Mora Guido C GC
Journal of bacteriology 20040501 10
The large pathogenicity island (SPI7) of Salmonella enterica serovar Typhi is a 133,477-bp segment of DNA flanked by two 52-bp direct repeats overlapping the pheU (phenylalanyl-tRNA) gene, contains 151 potential open reading frames, and includes the viaB operon involved in the synthesis of Vi antigen. Some clinical isolates of S. enterica serovar Typhi are missing the entire SPI7, due to its precise excision; these strains have lost the ability to produce Vi antigen, are resistant to phage Vi-II ...[more]
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