Ontology highlight
ABSTRACT:
SUBMITTER: Protti A
PROVIDER: S-EPMC4006866 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Protti Alessandro A Fortunato Francesco F Caspani Maria L ML Pluderi Mauro M Lucchini Valeria V Grimoldi Nadia N Solimeno Luigi P LP Fagiolari Gigliola G Ciscato Patrizia P Zella Samis M A SM Moggio Maurizio M Comi Giacomo P GP Gattinoni Luciano L
PloS one 20140501 5
Platelets can serve as general markers of mitochondrial (dys)function during several human diseases. Whether this holds true even during sepsis is unknown. Using spectrophotometry, we measured mitochondrial respiratory chain biochemistry in platelets and triceps brachii muscle of thirty patients with septic shock (within 24 hours from admission to Intensive Care) and ten surgical controls (during surgery). Results were expressed relative to citrate synthase (CS) activity, a marker of mitochondri ...[more]