Ontology highlight
ABSTRACT:
SUBMITTER: Zano SP
PROVIDER: S-EPMC4007306 | biostudies-literature | 2013 Aug
REPOSITORIES: biostudies-literature
Zano Stephen P SP Bhansali Pravin P Luniwal Amarjit A Viola Ronald E RE
Archives of biochemistry and biophysics 20130524 1
S-adenosyl-l-methionine (AdoMet) synthetase catalyzes the production of AdoMet, the major biological methyl donor and source of methylene, amino, ribosyl, and aminopropyl groups in the metabolism of all known organism. In addition to these essential functions, AdoMet can also serve as the precursor for two different families of quorum sensing molecules that trigger virulence in Gram-negative human pathogenic bacteria. The enzyme responsible for AdoMet biosynthesis has been cloned, expressed and ...[more]