Ontology highlight
ABSTRACT:
SUBMITTER: Arimatsu K
PROVIDER: S-EPMC4010932 | biostudies-literature | 2014 May
REPOSITORIES: biostudies-literature
Arimatsu Kei K Yamada Hitomi H Miyazawa Haruna H Minagawa Takayoshi T Nakajima Mayuka M Ryder Mark I MI Gotoh Kazuyoshi K Motooka Daisuke D Nakamura Shota S Iida Tetsuya T Yamazaki Kazuhisa K
Scientific reports 20140506
Periodontitis has been implicated as a risk factor for metabolic disorders such as type 2 diabetes, atherosclerotic vascular diseases, and non-alcoholic fatty liver disease. Although bacteremias from dental plaque and/or elevated circulating inflammatory cytokines emanating from the inflamed gingiva are suspected mechanisms linking periodontitis and these diseases, direct evidence is lacking. We hypothesize that disturbances of the gut microbiota by swallowed bacteria induce a metabolic endotoxe ...[more]