Ontology highlight
ABSTRACT:
SUBMITTER: Flowers GP
PROVIDER: S-EPMC4011087 | biostudies-literature | 2014 May
REPOSITORIES: biostudies-literature
Flowers G Parker GP Timberlake Andrew T AT McLean Kaitlin C KC Monaghan James R JR Crews Craig M CM
Development (Cambridge, England) 20140424 10
Among tetrapods, only urodele salamanders, such as the axolotl Ambystoma mexicanum, can completely regenerate limbs as adults. The mystery of why salamanders, but not other animals, possess this ability has for generations captivated scientists seeking to induce this phenomenon in other vertebrates. Although many recent advances in molecular biology have allowed limb regeneration and tissue repair in the axolotl to be investigated in increasing detail, the molecular toolkit for the study of this ...[more]