Clinical and economic outcomes associated with medication errors in kidney transplantation.

ABSTRACT:

Background and objectives

Modern immunosuppressant regimens have significantly decreased acute rejection rates, but may have increased the risk of graft loss driven by adverse drug reactions (ADRs) and medication errors (MEs). The objectives of this study were to determine the incidence and risk factors for MEs and ADRs and determine the association between transplant outcomes and these events.

Design, setting, participants, & measurements

This was a post hoc analysis of a prospective, randomized trial that included patients aged>18 years that received a solitary renal transplant at an academic medical center recruited between March 2009 and July 2011. Patients were divided into groups based on developing a clinical significant ME (CSME), defined as a significant ME that con

SUBMITTER: Taber DJ 

PROVIDER: S-EPMC4011453 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature