Development of rapidly evolving intron markers to estimate multilocus species trees of rodents.

ABSTRACT: One of the major challenges in the analysis of closely related species, speciation and phylogeography is the identification of variable sequence markers that allow the determination of genealogical relationships in multiple genomic regions using coalescent and species tree approaches. Rodent species represent nearly half of the mammalian diversity, but so far no systematic study has been carried out to detect suitable informative markers for this group. Here, we used a bioinformatic pipeline to extract intron sequences from rodent genomes available in databases and applied a series of filters that allowed the identification of 208 introns that adequately fulfilled several criteria for these studies. The main required characteristics of the introns were that they had the maximum possible mu

SUBMITTER: Rodriguez-Prieto A 

PROVIDER: S-EPMC4012946 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature