Ontology highlight
ABSTRACT:
SUBMITTER: Autio JA
PROVIDER: S-EPMC4013757 | biostudies-literature | 2014 May
REPOSITORIES: biostudies-literature
Autio Joonas A JA Shatillo Artem A Giniatullin Rashid R Gröhn Olli H OH
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20140205 5
We found novel types of parenchymal functional magnetic resonance imaging (fMRI) signals in the rat brain during large increases in metabolism. Cortical spreading depression (CSD), a self-propagating wave of cellular activation, is associated with several pathologic conditions such as migraine and stroke. It was used as a paradigm to evoke transient neuronal depolarization leading to enhanced energy consumption. Activation of CSD was investigated using spin-lock (SL), diffusion, blood oxygenatio ...[more]