Ontology highlight
ABSTRACT:
SUBMITTER: Terpstra M
PROVIDER: S-EPMC4013769 | biostudies-literature | 2014 May
REPOSITORIES: biostudies-literature
Terpstra Melissa M Moheet Amir A Kumar Anjali A Eberly Lynn E LE Seaquist Elizabeth E Öz Gülin G
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20140219 5
Hypoglycemia-associated autonomic failure (HAAF) is a condition in which patients with type 1 diabetes (T1D) who experience frequent hypoglycemia develop defective glucose counter-regulation and become unable to sense hypoglycemia. Brain glutamate may be involved in the mechanism of HAAF. The goal of this study was to follow the human brain glutamate concentration during experimentally induced hypoglycemia in subjects with and without HAAF. (1)H magnetic resonance spectroscopy was used to track ...[more]