Factors associated with early deterioration after spontaneous intracerebral hemorrhage: a systematic review and meta-analysis.

ABSTRACT:

Background and purpose

Spontaneous intracerebral hemorrhage (ICH) is a devastating form of stroke with a poor prognosis overall. We conducted a systematic review and meta-analysis to identify and describe factors associated with early neurologic deterioration (END) after ICH.

Methods

We sought to identify any factor which could be prognostic in the absence of an intervention. The Cochrane Library, EMBASE, the Global Health Library, and PubMed were searched for primary studies from the years 1966 to 2012 with no restrictions on language or study design. Studies of patients who received a surgical intervention or specific experimental therapies were excluded. END was defined as death, or worsening on a reliable outcome scale within seven days after onset.

Results

7,172

SUBMITTER: Specogna AV 

PROVIDER: S-EPMC4014549 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature