Ontology highlight
ABSTRACT:
SUBMITTER: Miller CL
PROVIDER: S-EPMC4015632 | biostudies-literature | 2014 May
REPOSITORIES: biostudies-literature
Miller Clint L CL Assimes Themistocles L TL Montgomery Stephen B SB Quertermous Thomas T
Current atherosclerosis reports 20140501 5
Large-scale genome-wide association studies (GWAS) have identified 46 loci that are associated with coronary heart disease (CHD). Additionally, 104 independent candidate variants (false discovery rate of 5 %) have been identified (Schunkert H, Konig IR, Kathiresan S, Reilly MP, Assimes TL, Holm H et al. Nat Genet 43:333-8, 2011; Deloukas P, Kanoni S, Willenborg C, Farrall M, Assimes TL, Thompson JR et al. Nat Genet 45:25-33, 2012; C4D Genetics Consortium. Nat Genet 43:339-44, 2011). The majority ...[more]