Ontology highlight
ABSTRACT:
SUBMITTER: Shin E
PROVIDER: S-EPMC4017031 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Shin Euikyung E Kashiwagi Yutaro Y Kuriu Toshihiko T Iwasaki Hirohide H Tanaka Teruyuki T Koizumi Hiroyuki H Gleeson Joseph G JG Okabe Shigeo S
Nature communications 20130101
Dendritic morphogenesis and formation of synapses at appropriate dendritic locations are essential for the establishment of proper neuronal connectivity. Recent imaging studies provide evidence for stabilization of dynamic distal branches of dendrites by the addition of new synapses. However, molecules involved in both dendritic growth and suppression of synapse maturation remain to be identified. Here we report two distinct functions of doublecortin-like kinases, chimeric proteins containing bo ...[more]