Unknown

Dataset Information

0

Preparation, gram-negative antibacterial activity, and hydrolytic stability of novel siderophore-conjugated monocarbam diols.


ABSTRACT: A novel series of monocarbam compounds exhibiting promising antibacterial activity against multidrug resistant Gram-negative microorganisms is reported, along with the synthesis of one such molecule MC-1 (1). Also reported are structure-activity relationships associated with the in vitro and in vivo efficacy of 1 and related analogues in addition to the hydrolytic stability of such compounds and possible implications thereof.

SUBMITTER: Flanagan ME 

PROVIDER: S-EPMC4018130 | biostudies-literature | 2011 May

REPOSITORIES: biostudies-literature

altmetric image

Publications


A novel series of monocarbam compounds exhibiting promising antibacterial activity against multidrug resistant Gram-negative microorganisms is reported, along with the synthesis of one such molecule MC-1 (1). Also reported are structure-activity relationships associated with the in vitro and in vivo efficacy of 1 and related analogues in addition to the hydrolytic stability of such compounds and possible implications thereof. ...[more]

Similar Datasets

| S-EPMC5740388 | biostudies-literature
| S-EPMC9000143 | biostudies-literature
| S-EPMC3294957 | biostudies-literature
| S-EPMC5760645 | biostudies-literature
| S-EPMC3754284 | biostudies-literature
| S-EPMC3497185 | biostudies-literature
| S-EPMC10135019 | biostudies-literature
| S-EPMC9505607 | biostudies-literature
| S-EPMC2876421 | biostudies-literature
| S-EPMC9463142 | biostudies-literature