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Catalytic asymmetric peroxidation of ?,?-unsaturated nitroalkenes by a bifunctional organic catalyst.

ABSTRACT: A new enantioselective peroxidation of ?,?-unsaturated nitroalkenes was realized with an easily accessible acid-base bifunctional organic catalyst derived from cinchona alkaloids. This reaction provides unprecedented easy access to optically active chiral peroxides, as illustrated by the asymmetric synthesis of ?-peroxy nitro compounds.

SUBMITTER: Lu X

PROVIDER: S-EPMC4018155 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature

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Catalytic asymmetric peroxidation of α,β-unsaturated nitroalkenes by a bifunctional organic catalyst.

Lu Xiaojie X Deng Li L

Organic letters 20140414 9

A new enantioselective peroxidation of α,β-unsaturated nitroalkenes was realized with an easily accessible acid-base bifunctional organic catalyst derived from cinchona alkaloids. This reaction provides unprecedented easy access to optically active chiral peroxides, as illustrated by the asymmetric synthesis of β-peroxy nitro compounds. ...[more]

PMID: 24730647

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