Assessment of volumetric growth rates of small colorectal polyps with CT colonography: a longitudinal study of natural history.

ABSTRACT:

Background

The clinical relevance and in-vivo growth rates of small (6-9 mm) colorectal polyps are not well established. We aimed to assess the behaviour of such polyps with CT colonography assessments.

Methods

In this longitudinal study, we enrolled asymptomatic adults undergoing routine colorectal cancer screening with CT colonography at two medical centres in the USA. Experienced investigators (PJP, DHK, JLH) measured volumes and maximum linear sizes of polyps in vivo with CT colonography scans at baseline and surveillance follow-up. We defined progression, stability, and regression on the basis of a 20% volumetric change per year from baseline (20% or more growth classed as progression, 20% growth to -20% reduction classed as stable, and -20% or more reduction classed as

SUBMITTER: Pickhardt PJ 

PROVIDER: S-EPMC4018232 | biostudies-literature | 2013 Jul

REPOSITORIES: biostudies-literature