Ontology highlight
ABSTRACT:
SUBMITTER: Calvanese V
PROVIDER: S-EPMC4019006 | biostudies-literature | 2013 Nov
REPOSITORIES: biostudies-literature
Virology 20130906 1-2
HIV latency constitutes the main barrier for clearing HIV infection from patients. Our inability to recognize and isolate latently infected cells hinders the study of latent HIV. We engineered two HIV-based viral reporters expressing different fluorescent markers: one HIV promoter-dependent marker for productive HIV infection, and a second marker under a constitutive promoter independent of HIV promoter activity. Infection of cells with these viruses allows the identification and separation of l ...[more]