Ontology highlight
ABSTRACT:
SUBMITTER: Gomez-Sebastian S
PROVIDER: S-EPMC4019511 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Gómez-Sebastián Silvia S López-Vidal Javier J Escribano José M JM
PloS one 20140513 5
Here we describe the development of a baculovirus vector expression cassette containing rearranged baculovirus-derived genetic regulatory elements. This newly designed expression cassette conferred significant production improvements to the baculovirus expression vector system (BEVS), including prolonged cell integrity after infection, improved protein integrity, and around 4-fold increase in recombinant protein production yields in insect cells with respect to a standard baculovirus vector. The ...[more]