Ontology highlight
ABSTRACT:
SUBMITTER: Hyland C
PROVIDER: S-EPMC4019958 | biostudies-literature | 2014 May
REPOSITORIES: biostudies-literature
Hyland Callen C Mertz Aaron F AF Forscher Paul P Dufresne Eric E
Scientific reports 20140514
Growth cones of elongating neurites exert force against the external environment, but little is known about the role of force in outgrowth or its relationship to the mechanical organization of neurons. We used traction force microscopy to examine patterns of force in growth cones of regenerating Aplysia bag cell neurons. We find that traction is highest in the peripheral actin-rich domain and internal stress reaches a plateau near the transition between peripheral and central microtubule-rich do ...[more]