Expression of TPM1?, a Novel Sarcomeric Isoform of the TPM1 Gene, in Mouse Heart and Skeletal Muscle.
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ABSTRACT:
SUBMITTER: Dube S
PROVIDER: S-EPMC4020292 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
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Expression of TPM1κ, a Novel Sarcomeric Isoform of the TPM1 Gene, in Mouse Heart and Skeletal Muscle.
Dube Syamalima S Panebianco Lauren L Matoq Amr A AA Chionuma Henry N HN Denz Christopher R CR Poiesz Bernard J BJ Dube Dipak K DK
Molecular biology international 20140424
We have investigated the expression of TPM1 α and TPM1 κ in mouse striated muscles. TPM1 α and TMP1 κ were amplified from the cDNA of mouse heart by using conventional RT-PCR. We have cloned the PCR amplified DNA and determined the nucleotide sequences. Deduced amino acid sequences show that there are three amino acid changes in mouse exon 2a when compared with the human TPM1 κ . However, the deduced amino acid sequences of human TPM1 α and mouse TPM1 α are identical. Conventional RT-PCR data as ...[more]
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