Ontology highlight
ABSTRACT:
SUBMITTER: Sumner JA
PROVIDER: S-EPMC4020959 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Sumner Jennifer A JA Vrshek-Schallhorn Suzanne S Mineka Susan S Zinbarg Richard E RE Craske Michelle G MG Redei Eva E EE Wolitzky-Taylor Kate K Adam Emma K EK
Cognition & emotion 20131216 5
Overgeneral autobiographical memory (OGM) is a key memory deficit in major depressive disorder (MDD). Much research has examined cognitive mechanisms underlying OGM, but little work has investigated potential neurobiological influences. There is preliminary evidence that a genetic serotonergic vulnerability coupled with depressive symptoms may be associated with other memory impairments, and experimental research suggests a role for serotonin in OGM. We investigated whether a polymorphism in the ...[more]