Dataset Information

Mortality risk associated with underweight: a census-linked cohort of 31,578 individuals with up to 32 years of follow-up.

ABSTRACT:

Background

In contrast to obesity, information on the health risks of underweight is sparse. We examined the long-term association between underweight and mortality by considering factors possibly influencing this relationship.

Methods

We included 31,578 individuals aged 25-74 years, who participated in population based health studies between 1977 and 1993 and were followed-up for survival until 2008 by record linkage with the Swiss National Cohort (SNC). Body Mass Index (BMI) was calculated from measured (53% of study population) or self-reported height and weight. Underweight was defined as BMI?ResultsUnderweight individuals represented 3.0% of the total study population (n?=?945), and were mostly women (89.9%). Compared to normal weight, underweight was associated with increased all-cause mortality (HR: 1.37; 95% CI: 1.14-1.65). Increased risk was apparent in both sexes, regardless of smoking status, and mainly driven by excess death from external causes (HR: 3.18; 1.96-5.17), but not cancer, cardiovascular or respiratory diseases. The HR were 1.16 (0.88-1.53) in studies with measured BMI and 1.59 (1.24-2.05) with self-reported BMI.

Conclusions

The increased risk of dying of underweight people was mainly due to an increased mortality risk from external causes. Using self-reported BMI may lead to an overestimation of mortality risk associated with underweight.

SUBMITTER: Roh L

PROVIDER: S-EPMC4021191 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Mortality risk associated with underweight: a census-linked cohort of 31,578 individuals with up to 32 years of follow-up.

Roh Lucienne L Braun Julia J Chiolero Arnaud A Bopp Matthias M Rohrmann Sabine S Faeh David D

BMC public health 20140416

<h4>Background</h4>In contrast to obesity, information on the health risks of underweight is sparse. We examined the long-term association between underweight and mortality by considering factors possibly influencing this relationship.<h4>Methods</h4>We included 31,578 individuals aged 25-74 years, who participated in population based health studies between 1977 and 1993 and were followed-up for survival until 2008 by record linkage with the Swiss National Cohort (SNC). Body Mass Index (BMI) was ...[more]

PMID: 24739374

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Dataset Information

Mortality risk associated with underweight: a census-linked cohort of 31,578 individuals with up to 32 years of follow-up.

Background

Methods

Conclusions

Publications

Mortality risk associated with underweight: a census-linked cohort of 31,578 individuals with up to 32 years of follow-up.

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