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Dynamics of soft nanomaterials captured by transmission electron microscopy in liquid water.

ABSTRACT: In this paper we present in situ transmission electron microscopy of synthetic polymeric nanoparticles with emphasis on capturing motion in a solvated, aqueous state. The nanoparticles studied were obtained from the direct polymerization of a Pt(II)-containing monomer. The resulting structures provided sufficient contrast for facile imaging in situ. We contend that this technique will quickly become essential in the characterization of analogous systems, especially where dynamics are of interest in the solvated state. We describe the preparation of the synthetic micellar nanoparticles together with their characterization and motion in liquid water with comparison to conventional electron microscopy analyses.

SUBMITTER: Proetto MT

PROVIDER: S-EPMC4021868 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature

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Dynamics of soft nanomaterials captured by transmission electron microscopy in liquid water.

Proetto Maria T MT Rush Anthony M AM Chien Miao-Ping MP Abellan Baeza Patricia P Patterson Joseph P JP Thompson Matthew P MP Olson Norman H NH Moore Curtis E CE Rheingold Arnold L AL Andolina Christopher C Millstone Jill J Howell Stephen B SB Browning Nigel D ND Evans James E JE Gianneschi Nathan C NC

Journal of the American Chemical Society 20140114 4

In this paper we present in situ transmission electron microscopy of synthetic polymeric nanoparticles with emphasis on capturing motion in a solvated, aqueous state. The nanoparticles studied were obtained from the direct polymerization of a Pt(II)-containing monomer. The resulting structures provided sufficient contrast for facile imaging in situ. We contend that this technique will quickly become essential in the characterization of analogous systems, especially where dynamics are of interest ...[more]

PMID: 24422495

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