Nonhomologous end joining: a good solution for bad ends.
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ABSTRACT:
SUBMITTER: Waters CA
PROVIDER: S-EPMC4024359 | biostudies-literature | 2014 May
REPOSITORIES: biostudies-literature
Publications
Nonhomologous end joining: a good solution for bad ends.
Waters Crystal A CA Strande Natasha T NT Wyatt David W DW Pryor John M JM Ramsden Dale A DA
DNA repair 20140314
Double strand breaks pose unique problems for DNA repair, especially when broken ends possess complex structures that interfere with standard DNA transactions. Nonhomologous end joining can use multiple strategies to solve these problems. It further uses sophisticated means to ensure the strategy chosen provides the ideal balance of flexibility and accuracy. ...[more]
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