Ontology highlight
ABSTRACT:
SUBMITTER: Zaanan A
PROVIDER: S-EPMC4026996 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Zaanan Aziz A Dalban Cécile C Emile Jean-François JF Blons Hélène H Fléjou Jean-François JF Goumard Claire C Istanbullu Melek M Calmel Claire C Alhazmi Khalid K Validire Pierre P Louvet Christophe C de Gramont Aimery A Laurent-Puig Pierre P Taïeb Julien J Praz Françoise F
Journal of Cancer 20140502 6
<h4>Background</h4>While single nucleotide polymorphisms (SNP) in genes involved in DNA repair or drug metabolism have been shown to influence survival of metastatic colon cancer patients treated with FOLFOX, data on adjuvant setting are scarce.<h4>Methods</h4>This study evaluated the correlation between disease-free survival (DFS) of 210 unselected stage III colon cancer patients receiving FOLFOX chemotherapy, and ERCC1-118 (rs11615, c.354T>C), XRCC1-399 (rs25487, c.1196G>A) and GSTP1-105 (rs16 ...[more]