Ontology highlight
ABSTRACT:
SUBMITTER: Richman TR
PROVIDER: S-EPMC4027184 | biostudies-literature | 2014 May
REPOSITORIES: biostudies-literature
Richman Tara R TR Davies Stefan M K SM Shearwood Anne-Marie J AM Ermer Judith A JA Scott Louis H LH Hibbs Moira E ME Rackham Oliver O Filipovska Aleksandra A
Nucleic acids research 20140305 9
Mitochondrial gene expression is predominantly regulated at the post-transcriptional level and mitochondrial ribonucleic acid (RNA)-binding proteins play a key role in RNA metabolism and protein synthesis. The AU-binding homolog of enoyl-coenzyme A (CoA) hydratase (AUH) is a bifunctional protein with RNA-binding activity and a role in leucine catabolism. AUH has a mitochondrial targeting sequence, however, its role in mitochondrial function has not been investigated. Here, we found that AUH loca ...[more]