Original Design of Fluorescent Ligands by Fusing BODIPY and Melatonin Neurohormone.
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ABSTRACT:
SUBMITTER: Thireau J
PROVIDER: S-EPMC4027590 | biostudies-literature | 2014 Feb
REPOSITORIES: biostudies-literature
Publications
Original Design of Fluorescent Ligands by Fusing BODIPY and Melatonin Neurohormone.
Thireau Jérémy J Marteaux Justine J Delagrange Philippe P Lefoulon Francois F Dufourny Laurence L Guillaumet Gérald G Suzenet Franck F
ACS medicinal chemistry letters 20131120 2
An original design and synthesis of fluorescent ligands for melatonin receptor studies is presented and consists in the fusion of the endogenous ligand with the fluorescent BODIPY core. Probes I-IV show high affinities for MT1 and MT2 melatonin receptors and exhibit fluorescence properties compatible with cell observation. ...[more]
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