Risk prediction of cardiovascular death based on the QTc interval: evaluating age and gender differences in a large primary care population.

ABSTRACT:

Aims

Using a large, contemporary primary care population we aimed to provide absolute long-term risks of cardiovascular death (CVD) based on the QTc interval and to test whether the QTc interval is of value in risk prediction of CVD on an individual level.

Methods and results

Digital electrocardiograms from 173 529 primary care patients aged 50-90 years were collected during 2001-11. The Framingham formula was used for heart rate-correction of the QT interval. Data on medication, comorbidity, and outcomes were retrieved from administrative registries. During a median follow-up period of 6.1 years, 6647 persons died from cardiovascular causes. Long-term risks of CVD were estimated for subgroups defined by age, gender, cardiovascular disease, and QTc interval categories. In ge

SUBMITTER: Nielsen JB 

PROVIDER: S-EPMC4028611 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature