Red Si-rhodamine drug conjugates enable imaging in GFP cells.
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ABSTRACT:
SUBMITTER: Kim E
PROVIDER: S-EPMC4028821 | biostudies-literature | 2014 May
REPOSITORIES: biostudies-literature
Publications
Red Si-rhodamine drug conjugates enable imaging in GFP cells.
Kim Eunha E Yang Katherine S KS Giedt Randy J RJ Weissleder Ralph R
Chemical communications (Cambridge, England) 20140325 34
Here we evaluated a series of Si-derivatized rhodamine (SiR) dyes for their ability to visualize a model drug in live cells. We show that a charge neutral SiR derivative (but not others) can indeed be used to follow the intracellular location of the model therapeutic drug in GFP cells. ...[more]
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