Ontology highlight
ABSTRACT:
SUBMITTER: Chuong EB
PROVIDER: S-EPMC4031627 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
Chuong Edward B EB Tong Wenfei W Hoekstra Hopi E HE
Molecular biology and evolution 20100201 6
Conflicting evolutionary interests between mother and offspring are hypothesized to drive an evolutionary arms race during mammalian pregnancy, and thus, positive selection may cause the rapid divergence of placental proteins that affect maternal or fetal fitness. We investigated the genomic consequences of placental expression in rodents and report that a substantial proportion (20.5%) of genes specifically expressed in the mature placenta are rapidly evolving. Moreover, we found that most rapi ...[more]