Sequencing Y chromosomes resolves discrepancy in time to common ancestor of males versus females.
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ABSTRACT:
SUBMITTER: Poznik GD
PROVIDER: S-EPMC4032117 | biostudies-literature | 2013 Aug
REPOSITORIES: biostudies-literature
Publications
Sequencing Y chromosomes resolves discrepancy in time to common ancestor of males versus females.
Poznik G David GD Henn Brenna M BM Yee Muh-Ching MC Sliwerska Elzbieta E Euskirchen Ghia M GM Lin Alice A AA Snyder Michael M Quintana-Murci Lluis L Kidd Jeffrey M JM Underhill Peter A PA Bustamante Carlos D CD
Science (New York, N.Y.) 20130801 6145
The Y chromosome and the mitochondrial genome have been used to estimate when the common patrilineal and matrilineal ancestors of humans lived. We sequenced the genomes of 69 males from nine populations, including two in which we find basal branches of the Y-chromosome tree. We identify ancient phylogenetic structure within African haplogroups and resolve a long-standing ambiguity deep within the tree. Applying equivalent methodologies to the Y chromosome and the mitochondrial genome, we estimat ...[more]
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