Ontology highlight
ABSTRACT:
SUBMITTER: Clapham HE
PROVIDER: S-EPMC4032531 | biostudies-literature | 2014 Jul
REPOSITORIES: biostudies-literature
Clapham Hannah E HE Tricou Vianney V Van Vinh Chau Nguyen N Simmons Cameron P CP Ferguson Neil M NM
Journal of the Royal Society, Interface 20140701 96
Dengue, the most common mosquito-borne viral infection of humans, is endemic across much of the world, including much of tropical Asia and is increasing in its geographical range. Here, we present a mathematical model of dengue virus dynamics within infected individuals, detailing the interaction between virus and a simple immune response. We fit this model to measurements of plasma viral titre from cases of primary and secondary DENV 1 infection in Vietnam. We show that variation in model param ...[more]