Assessment of plasma C-reactive protein as a biomarker of posttraumatic stress disorder risk.

ABSTRACT:

Importance

Posttraumatic stress disorder (PTSD) has been associated in cross-sectional studies with peripheral inflammation. It is not known whether this observed association is the result of PTSD predisposing to inflammation (as sometimes postulated) or to inflammation predisposing to PTSD.

Objective

To determine whether plasma concentration of the inflammatory marker C-reactive protein (CRP) helps predict PTSD symptoms.

Design, setting, and participants

The Marine Resiliency Study, a prospective study of approximately 2600 war zone-deployed Marines, evaluated PTSD symptoms and various physiological and psychological parameters before deployment and at approximately 3 and 6 months following a 7-month deployment. Participants were recruited from 4 all-male infantry ba

SUBMITTER: Eraly SA 

PROVIDER: S-EPMC4032578 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature