Ontology highlight
ABSTRACT:
SUBMITTER: Corrales J
PROVIDER: S-EPMC4032594 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
Corrales J J Fang X X Thornton C C Mei W W Barbazuk W B WB Duke M M Scheffler B E BE Willett K L KL
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20140224
Benzo[a]pyrene (BaP) is an established carcinogen and reproductive and developmental toxicant. BaP exposure in humans and animals has been linked to infertility and multigenerational health consequences. DNA methylation is the most studied epigenetic mechanism that regulates gene expression, and mapping of methylation patterns has become an important tool for understanding pathologic gene expression events. The goal of this study was to investigate aberrant changes in promoter DNA methylation in ...[more]