Ontology highlight
ABSTRACT:
SUBMITTER: D'Onofrio DJ
PROVIDER: S-EPMC4033003 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
D'Onofrio David J DJ Abel David L DL
Frontiers in genetics 20140520
The codon redundancy ("degeneracy") found in protein-coding regions of mRNA also prescribes Translational Pausing (TP). When coupled with the appropriate interpreters, multiple meanings and functions are programmed into the same sequence of configurable switch-settings. This additional layer of Ontological Prescriptive Information (PIo) purposely slows or speeds up the translation-decoding process within the ribosome. Variable translation rates help prescribe functional folding of the nascent pr ...[more]